Infectious Diseases

HCV Lifecycle

How the hepatitis C virus (HCV) infects the liver

The HCV is usually transmitted through blood-to-blood contact. The virus replicates in the hepatocytes of the liver and circulates throughout the body.

Entry into hepatocytes occurs through the interaction of the viral envelope with receptors on the surface of the host cell. The virus undergoes a fusion and uncoating step, releasing positive-strand viral RNA. HCV utilizes many of the host cell’s proteins and molecules in order to replicate.


We have created this 3D visual of the Coronavirus using the latest research available. For this overall representation surface protein density has been reduced to help show spike, envelope, and membrane proteins.

We would like to give it to publications and news outlets for free with Fusion Animation as an image credit. If you would like a high resolution image or this animation please email