This Fusion Animation uses 3D medical animation to illustrate the Mechanism of Action (MOA) of EDIT-301, a gene-editing medicine for Sickle Cell Disease (SCD) and Beta-Thalassemia (TDT). The video visualizes the pathophysiology and shows how EDIT-301 uses a nuclease to edit the fetal hemoglobin gene promoter. This drives the sustained production of fetal hemoglobin, correcting anemia. This showcases our expertise in Gene Therapy and Hematology.

This Fusion Animation details bit.bio's revolutionary opti-ox™ technology for cell manufacturing. We used a minimalist style to show the cell as a computer, and how opti-ox overcomes gene silencing by inserting new programs into Genomic Safe Harbour sites. This proprietary method enables the deterministic, scalable manufacturing of pure human cells (e.g., ioGlutamatergic Neurons) for drug discovery and cell therapies. This showcases our expertise in Cell Reprogramming and Biotechnology