This Fusion Animation for patients and carers uses 3D medical animation to illustrate the Pathophysiology and Mechanism of Disease (MOD) for Fabry disease, a genetic lysosomal storage disorder. We visualize the core defect: a missing alpha-GAL enzyme. This deficiency causes the toxic, progressive accumulation of the fatty substance GL-3 within cells and organs, leading to severe organ damage. This showcases our expertise in visualizing complex concepts in Rare Genetic Diseases.